Diaper cream, particularly those containing zinc oxide like Desitin, can be a formidable foe when it comes to laundry. These creams are designed to create a barrier, which, while effective for protecting skin, can translate into stubborn stains on clothing. This guide will walk you through effective methods for removing these challenging marks, even after they’ve been through the wash.
Understanding Diaper Cream Stains
Diaper creams are primarily composed of ingredients that create a thick, often greasy, paste. The zinc oxide component is particularly notorious for its ability to adhere to fabric fibers. The challenge is compounded when stained items are machine-dried, as the heat can set the stain, making it significantly harder to remove.

Initial Steps for Stain Removal
Before reaching for specific cleaning products, the first and most crucial step is to remove as much of the excess diaper cream as possible. This should be done carefully to avoid spreading the stain further into the fabric.
- Wipe Away Excess Cream: Use paper towels or clean rags to gently blot and lift the bulk of the diaper cream from the fabric surface. Avoid rubbing at this stage, as it can push the cream deeper into the fibers.
- Avoid Moisture Initially: It’s best to avoid introducing water or other liquids until you have removed the majority of the thick cream. Moisture can dilute the cream and make it harder to lift away.
Choosing the Right Stain Removal Products
Once the excess cream has been removed, you can address the remaining stain. The type of product you choose will depend on the nature of the stain (often greasy) and the fabric composition.
Degreasers and Dish Soaps
Many diaper creams leave behind a grease stain. Products designed to cut through grease are often effective.
- Dish Soap: In a pinch, a good grease-cutting dish soap, such as Dawn, can be a starting point. Gently massage a small amount into the stain.
- Specialized Degreasers: For more stubborn stains, consider using commercial degreasers like De-Solv-It or CitraSolv. Older, yet effective, options include Lestoil and Pine-Sol.
Note for HE Washers: If you use a High-Efficiency (HE) washing machine, be mindful of the strong scents from products like Lestoil and Pine-Sol. Due to the low-water cycle in HE machines, these odors can linger. To mitigate this, you can either use an alternative product, use these products very sparingly, or run an additional rinse cycle with a small amount of Dr. Bronner’s soap to help neutralize strong smells.
Rubbing Alcohol and White Vinegar
For stains specifically caused by zinc oxide, rubbing alcohol can be a highly effective solution.
- Rubbing Alcohol: This is particularly good for zinc-based stains. Rubbing alcohol, especially in a spray bottle, can be a game-changer for stain removal. If you don't have a spray bottle, you can decant rubbing alcohol into one for easier application.
- Application Technique: For launderable fabrics, spray the affected area generously with rubbing alcohol. Hold the stained section taut under cold running water. Rub the fabric against itself under the stream of water, reapplying alcohol as needed.
- Washing and Drying: After treating the stain, wash the garment as usual. It is highly recommended to allow the item to air dry. Air drying is crucial because a wet garment can hide a lingering grease stain, and the heat from a dryer can permanently set any remaining discoloration.
- White Vinegar: White vinegar can also be used on diaper cream stains, though the application method differs slightly. Start by applying dish soap and massaging it into the stain, ideally with a toothbrush.

Commercial Stain Removers
While general laundry pre-treatment products might not always be sufficient for the unique nature of diaper cream stains, some specific products have shown promise.
- Spray 'n Wash and Shout: Research indicates that products like Spray 'n Wash Stain Stick and Shout spray have been successful for some parents in removing diaper cream stains.
- Enhancing Effectiveness: To maximize the effectiveness of these products, use a toothbrush or a laundry brush to work the product thoroughly into the stain before laundering the item.
General Tips for Diaper Cream Stain Removal
- Act Quickly: The sooner you address a diaper cream stain, the higher your chances of complete removal.
- Check Before Drying: Always inspect the stained area after washing and before putting the garment in the dryer. If the stain persists, repeat the treatment process.
- Consider Fabric Type: Always check the garment's care label and test any cleaning product on an inconspicuous area of the fabric first to ensure it won't cause damage or discoloration.